Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly .. Luiz A CR, Romualdo S LT, Fava A S. Angiofibroma nasofaríngeo: revisão de literatura. Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.
|Country:||Central African Republic|
|Published (Last):||24 March 2007|
|PDF File Size:||13.91 Mb|
|ePub File Size:||9.96 Mb|
|Price:||Free* [*Free Regsitration Required]|
Juvenile nasopharyngeal angiofibroma
Thus, early diagnosis, accurate staging and adequate treatment are essential in the management of this lesion. However, as in any invasive procedure, embolization presents risks that should be fully explained to the patients Mesothelioma Malignant solitary fibrous tumor.
Antral sign or Holman-Miller sign forward bowing of posterior wall of maxilla is pathognomic of angiofibroma. These classifications are very important in helping surgeons decide the appropriate surgical approach. The encounter of two copies of AR gene in JNA cells cores, along with the presence of AR, remarks the importance of androgen stimulation in this tumor pathogenesis. The tumor invades the infratemporal fossa or orbit without intracranial involvement.
The combination of different accesses to the tumor can be required 9.
Endoscopic Ressection of Juvenile Angiofibroma: Angiofibromaa control of bleeding during the resection of nasopharyngeal angiofibromas can be achieved successfully by temporary clamping of the external carotid arteries in the neck Genetic nasofaringgeo in juvenile nasopharyngeal angiofibromas. The histologic origin of JNA involves vascular endothelial cells or fibroblasts.
Exclusively endoscopic removal of juvenile nasopharyngeal angiofibroma: Recent angioibroma and genetic studies throw some light on this topic.
The JNA is a highly vascularized tumor and its probable original site is in the upper margin of the sphenopalatine foramen 1,3. A comparative study of surgical approches. Many studies highlight the benefit of preoperative arterial embolization to control bleeding intraoperative 16,29, Arch Pathol Lab Med ; Long-term tumor recurrence has been reported due to incomplete initial resection.
Pathology Outlines – Nasopharyngeal angiofibroma
Impaired Eustachian tube function, facial deformity, proptosis and changes in visual acuity may be seen. Juvenile nasopharyngeal angiofibroma NAJ is a tumor with vascular component, slow growing, benign but very aggressive because of its local invasiveness.
Improvements in surgical techniques are designed to shorten surgical time and thereby reduce patient morbidity.
The color depends on the vascular component and may vary from pale white in less vascular lesions to a pink and wine colored mass in highly vascularized ones.
JNA is benign but locally destructive.
Open in a separate window. Article accepted in April 21, We performed a columellar incision intersects similar to access to the perichondrium of the septum septoplasty nasoangiofibroma the opposite side. Sanchez de Guzman G. Find articles by Francis Vinicius Fontes de Lima.
Molecular factors Too little is known about the growth factors involved in the JNA pathogenesis, and its initiation and progression mechanisms are not very well known. The most significant risk is blindness, angipfibroma patients with occlusion of the ophthalmic or middle cerebral artery through the collateral circulation. Avid enhancement is noted on contrast-enhanced CT. Otolaryngol Head Neck Surg.
Endoscopic Surgery of Nasopharyngeal Angiofibroma
The most solid basic knowledge regarding the JNA is pursuant to its histology. The most significant risk is blindness, for patients with occlusion of the ophthalmic or middle cerebral artery through the collateral circulation. Arterial embolization in the management of posterior epistaxis.
To remove the tumor in two angiofinroma, the tumor section was performed in two halves, the largest of which was removed by transoral route.
Since an abnormality in the hypothalamic axis was proposed by Schif 38as a JNA pathogenesis theory, the expression of hormonal receptors in the JNA has already been the nasogaringeo of many studies. In spite of the existing controversy, the hormonal stimulation means remains a JNA therapeutic possible target. Nasopharyngeal angiofibroma also called juvenile nasopharyngeal angiofibroma   is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity.